Lecture — Protein Design Part I

This session introduces Protein Design foundations: what sequence/structure information is, how to find it, and how modern ML tools have changed design workflows.

Core resources (converted from the course page)

  • RCSB PDB — archive and tools for experimentally-determined macromolecular structures, with powerful search/visualization.
  • UniProt / UniProtKB — comprehensive, curated protein sequence and functional knowledgebase; tightly linked with PDB and other resources.
  • Predicted structures — both resources now surface computationally predicted structures for many proteins, complementing experimental data.

(Slides and recording will be posted here when available.)