Projects

Peptide therapeutic design targeting Cyclophilin D to block mPTP opening in ischemia–reperfusion injury—computational design now, with planned in vitro/in vivo validation and iterative optimization.

MS2 lysis concept—separate L-protein N- and C-termini by introducing a stop in a 33-nt non-overlapping window to preserve overlapping cp/rep genes and enable DnaJ-independent C-terminal function.