HTGAA 2026 · Synthetic Biology · Lake Budi, La Araucanía, Chile
Füzi Poiesis
Topological Biocontainment for the Bioremediation of Lake Budi
Lake Budi is a brackish coastal lake in Lafkenche territory, La Araucanía — the largest coastal lake in Chile — facing compounding ecological crisis: benthic anoxia driven by halocline stratification, internal phosphorus loading, H₂S accumulation, and fecal coliform contamination documented at 54× the regulatory limit.
Füzi Poiesis proposes a three-strain synthetic bacterial consortium in which each strain targets one documented pathology, and the three strains are coupled through a circular cross-auxotrophic hypercycle — making biocontainment a structural property of the population topology, not a genetic kill switch. If any single strain escapes, the metabolic cycle collapses: the ring fails closed; a pair fails open.
Explore the full project →
