<Riu Yanagida> — HTGAA Spring 2026

About me
I am a high school student based in Japan. Currently, I am participating in HTGAA 2026, where I am exploring the fascinating intersection of synthetic biology and neuroscience.
👨‍🔬 Project: ARM-Net
My main research focus is ARM-Net. I want to shift the treatment of neurodegenerative diseases from simply “slowing down progression” to “active recovery.” My approach involves using CCT4 to strengthen microglia and build a network that efficiently clears toxic aggregates in the brain via Tunneling Nanotubes (TNTs).
Since the brain is a delicate ecosystem, I place the highest priority on “Temporal Reversibility” (being able to turn the system off) and “Ecological Homeostasis” (not disrupting the brain’s natural balance).
Human neuronal cells connected by a nanotube. © Anna Pepe/Institut Pasteur
🎸 Music & Hobbies
When I’m not studying biology, I’m usually immersed in music. I’m a multi-instrumentalist playing both guitar and bass.
My favorite bands include Van Halen, Led Zeppelin, Eagles, Lynyrd Skynyrd, Radiohead, Nirvana, RHCP, and NOFX. I love exploring different sounds and styles across these artists. If you share any of these musical tastes, please feel free to reach out—I’d love to chat!

✉️ A Note to My Colleagues
I am still working on my spoken English, so I find it a bit difficult to follow fast conversations. I would really appreciate it if we could communicate through text (Slack, Discord, or Email) whenever possible. As a high school student, I don’t have much experience with professional lab equipment yet. I am still in the early stages of my “wet-lab” journey. While I may lack experience, I have plenty of drive and a proactive attitude! I am eager to learn from all of you and move this project forward step by step.
Nice to meet you all