Homework

Week 1 HW: Principles and Practices
Assignment (Week 2 Lecture Prep) Homework Questions from Professor Jacobson: [Lecture 2 slides] Nature’s machinery for copying DNA is called polymerase. What is the error rate of polymerase? How does this compare to the length of the human genome. How does biology deal with that discrepancy? Polymerase has 1:106 error rate, while the human genome is 3x109 base pairs. This is dealt with by exonuclease proofreading, followed by postreplication mismatch repair that looks for erros.