Projects

Final projects:

  • #MycoTint: Stress Responsive Mycelium MycoTint is the conceptualization, genetic engineering, and biofabrication of reactive, living mycelium furniture capable of displaying visible color changes in response to mechanical stress. The objective is to engineer a mechanosensitive synthetic genetic circuit within the fungal host that actuates the expression of vivid, naked-eye-visible chromoproteins when specific points of the furniture are subjected to weight or impact. This document details the selection of the optimal biological chassis, the intricate design of the synthetic genetic circuit, fungal transformation protocols, specialized biofabrication and long-term viability maintenance strategies, practical feasibility assessments, alternative non-biological methods, and an analysis of precedent projects shaping the ELM landscape.
  • from Part D — Group Brainstorm on Bacteriophage Engineering (Individual submission — solo student)

    1. Project Goal The primary goal of this project is to increase the structural stability of the MS2 bacteriophage lysis protein (L-protein), with a secondary goal of reducing its dependency on the host chaperone DnaJ, while preserving its capacity to lyse bacterial cells through membrane pore formation.