Hi! I’m Arely Simon Gonzalo, a former student of the Colegio de Alto Rendimiento (COAR) Ica. I am currently an aspiring medical student with a deep passion for healthcare and the future of science.
I joined HTGAA because it represents a unique opportunity to learn directly from world-class experts. I am eager to explore the intersection of medicine and technology, as I believe that understanding life at a molecular and synthetic level is key to the next generation of medical breakthroughs.
Interests & Goals
Medicine: My primary focus and future career path. I am interested in how bioengineering can improve patient outcomes.
Biotechnology: I am fascinated by the potential of living systems to solve global challenges.
Bioplasts/Biomaterials: I am particularly interested in deepening my knowledge of bioplasts and their applications in sustainable science.
Collaborative Learning: I am ready to push my boundaries and contribute to this amazing global community.
Contact Information
I’m always open to connecting with fellow students and researchers!
Application: A low-cost, portable paper-based biosensor for detecting lead (Pb) in drinking water using engineered bacteria.
Why: Lead contamination in water is a global health crisis. Existing laboratory tests are expensive and slow. A portable biosensor would allow communities to test their own water instantly and affordably.
2. Governance and Policy Goals
The primary goal is to ensure Non-malfeasance (preventing harm) by ensuring the engineered bacteria do not escape into the environment.
Sub-goal A: Implement a biological “kill-switch” so bacteria cannot survive outside the test strip.
Sub-goal B: Establish a clear disposal protocol for used sensors to prevent environmental accumulation.
3. Governance Actions
Action 1: Technical Biocontainment (Design-based)
Purpose: To prevent the accidental spread of engineered organisms.
Design: Researchers must incorporate an auxotrophic strain (bacteria that need a specific nutrient not found in nature to survive).
Assumptions: Assumes the bacteria will not undergo a mutation that bypasses the kill-switch.
Risks: Success could lead to a false sense of security; if the kill-switch fails, the organism could persist in the wild.
Purpose: Create a mandatory labeling and disposal standard for bio-based consumer products.
Design: Federal regulatory bodies (like the EPA or local health ministries) must approve the packaging, which must include a biohazard return envelope.
Assumptions: Assumes users will follow instructions and not throw the strips in regular trash.
Risks: High costs of logistics for return programs might discourage companies from developing the tool.
Action 3: Community Training Programs (Incentive-based)
Purpose: To educate local actors on safe handling.
Design: Academic researchers partner with local NGOs to provide training and certification for “Community Water Leads.”
Assumptions: Assumes local leaders have the time and resources to participate.
Risks: If training is too complex, it creates a barrier to access, defeating the goal of “low-cost” equity.
4. Scoring Rubric
Goal / Action
Action 1 (Technical)
Action 2 (Regulatory)
Action 3 (Training)
Improve Biosecurity
1
2
3
Protect Environment
1
1
2
Feasibility
2
3
1
Promote Constructive Use
3
3
1
(Scale: 1 = Best/Most Effective, 3 = Least Effective/Hardest)
5. Selection and Trade-offs
I would prioritize a combination of Action 1 and Action 3.
Why: Technical biocontainment (Action 1) is the most reliable way to prevent environmental harm regardless of user behavior. However, it must be paired with Community Training (Action 3) to ensure the tool is used correctly and reaches the people who need it most. The main trade-off is the cost of training, but this is necessary to ensure ethical implementation and trust within the community.
6. Ethical Reflection
This week, I realized that “success” in bioengineering isn’t just about the science working; it’s about the social and ethical “scaffolding” around it. A new concern for me is the Equity of Access: if we create powerful tools but only rich countries can afford the governance/safety systems for them, we increase the global inequality gap. My proposed actions aim to balance safety with ease of use for marginalized communities.