<?xml version="1.0" encoding="utf-8" standalone="yes"?><rss version="2.0" xmlns:atom="http://www.w3.org/2005/Atom"><channel><title>Week 1 HW: Principles and Practices :: 2026a-aryan-boruah</title><link>https://pages.htgaa.org/2026a/aryan-boruah/homework/week-01-hw-principles-and-practices/index.html</link><description>Question 1:
Biological Engineering Application / Tool A Multiscale Computational Platform for Predictive Tissue Morphogenesis. I want to develop a computational–experimental platform that predicts tissue-level morphogenesis from gene regulatory, cellular, and mechanical inputs, with a particular focus on developmental defects and regenerative biology.
The core of the tool would integrate:
Single-cell transcriptomics and spatial transcriptomics (to capture gene expression states). Agent-based models (e.g cellular Potts or vertex models) to represent cell–cell interactions, division, and differentiation. Continuum mechanics (ECM stiffness gradients, stress fields) to model tissue-scale forces. The platform would allow researchers to simulate counterfactual interventions—for example:</description><generator>Hugo</generator><language>en</language><atom:link href="https://pages.htgaa.org/2026a/aryan-boruah/homework/week-01-hw-principles-and-practices/index.xml" rel="self" type="application/rss+xml"/></channel></rss>