https://pages.htgaa.org/2026a/ashish-srivastava/homework/week-05-hw-protein-design-part-ii/index.htmlTable of Contents Part A: SOD1 Binder Peptide Design Part B: BRD4 Drug Discovery Platform Tutorial Part C: Final Project: L-Protein Mutants Part A: SOD1 Binder Peptide Design Part 1: Generate Binders with PepMLM UniProt P00441 without the header: MATKAVCVLKGDGPVQGIINFEQKESNGPVKVWGSIKGLTEGLHGFHVHEFGDNTAGCTSAGPHFNPLSRKHGGPKDEERHVGDLGNVTADKDGVADVSIEDSVISLSGDHCIIGRTLVVHEKADDLGKGGNEESTKTGNAGSRLACGVIGIAQ The mutation “A4V” means the alanine at codon 4 (position) is changed to a valine. The M at the beginning is Methionine (coded by the codon AUG) but this is commonly ignored in canonical numbering since it’s the start codon. It’s there to signal the start of protein translation.Hugoen