Homework
Weekly homework submissions:
Week 1 HW: Principles and Practices
Biological engineering application or tool you want to develop and why. Functional thyroid hormone biosensing Thyroid hormones play a central role in human physiology. The thyroid gland produces thyroxine (T4; 3,3′,5,5′-tetraiodo-L-thyronine) and triiodothyronine (T3; 3,3′,5-triiodo-L-thyronine), of which T3 is the biologically active form. T3 regulates energy homeostasis, metabolism, growth, and normal development by controlling transcriptional programs across multiple tissues. Disruptions in thyroid hormone signaling therefore can cause severe consequences. For people with thyroid-related disorders is neccesary then to monitore their hormone levels frequently and “play” with the doses until they obtain a precise amount that doesnt trigger any negative effects.
Week 2 HW: DNA READ WRITE AND EDIT
Part 1: Benchling & In-silico Gel Art Rectriction enzymes used: EcoRI HindIII BamHI KpnI EcoRV SacI SalI I create a pattern that simulates angel feathers in benchling. I use the tool https://rcdonovan.com/gel-art to guide me c: Part 3: DNA Design Challenge 3.1. Choose your protein = Ferrochelatase Recently I have been reading about therapeutics that target mitochondria. Specifically in the paper of Corson Lab they mention about this protein that when is inhibited causes mitochondrial dysfunction and this is benefitial for anti-angiogenesis purposes in retinal pathologies.
Python Script for Opentrons For this assignment, we were expected to create an artwork using OpenTrons. I decided to draw an artistic eye with my name on the bottom. The desgin was created through the GUI page and was edited appropriately to run on Google Colab. The final design, after passing through the simulator, looks like this!
Week 4 HW: Protein Design Part 1
Part A. Conceptual Questions Question from Shuguang Zhang: Question 1 How many molecules of amino acids do you take with a piece of 500 grams of meat? (on average an amino acid is ~100 Daltons)