Homework

Weekly homework submissions:

• Week 1 HW: Principles and Practices

  Biological engineering application or tool you want to develop and why. Functional thyroid hormone biosensing Thyroid hormones play a central role in human physiology. The thyroid gland produces thyroxine (T4; 3,3′,5,5′-tetraiodo-L-thyronine) and triiodothyronine (T3; 3,3′,5-triiodo-L-thyronine), of which T3 is the biologically active form. T3 regulates energy homeostasis, metabolism, growth, and normal development by controlling transcriptional programs across multiple tissues. Disruptions in thyroid hormone signaling therefore can cause severe consequences. For people with thyroid-related disorders is neccesary then to monitore their hormone levels frequently and “play” with the doses until they obtain a precise amount that doesnt trigger any negative effects.

• Week 2 HW: DNA READ WRITE AND EDIT

  Part 1: Benchling & In-silico Gel Art Rectriction enzymes used: EcoRI HindIII BamHI KpnI EcoRV SacI SalI I create a pattern that simulates angel feathers in benchling. I use the tool https://rcdonovan.com/gel-art to guide me c: Part 3: DNA Design Challenge 3.1. Choose your protein = Ferrochelatase Recently I have been reading about therapeutics that target mitochondria. Specifically in the paper of Corson Lab they mention about this protein that when is inhibited causes mitochondrial dysfunction and this is benefitial for anti-angiogenesis purposes in retinal pathologies.