Homework
Weekly homework submissions:
Week 1 HW: Principles and Practices
Part 1: Yeast BioShields: Engineering Yeast for Wound Protection The global problem of multi-drug-resistant bacteria (MDR) has been a widespread issue for many years now. The World Health Organization has declared this phenomenon as a major global health threat, further emphasizing the need for a solution to this problem (Renata Urban-Chmiel et al, 2022). In the pursuit of this solution, I structured my idea around a way to reduce the threat of antibiotic-resistant bacteria.
Week 2 HW: DNA read, write and edit
Part 1: Benchling & In-silico Gel Art In order to create my gel art, I first created an account in Benchling and signed into it. Then, I found and downloaded the genebank of the Lambda DNA from New England Biolabs. After that, I simply pasted the DNA sequence into my Benchling workspace, and started experimenting with the different digestions possible using the allowed enzymes.
Part 01: Python Script for Opentrons Artwork In order to create my art, I use the Automation Art Interface, and uploaded my art into the required form. Part 02: Post-Lab Questions Question one: I belive a perfect example of a paper with automated lab use would be one that is also focused on it. Therefore, I found and read the 2019 research paper “Towards a fully automated algorithm driven platform for biosystems design” by Mohammad HamediRad (https://www.nature.com/articles/s41467-019-13189-z). This paper demonstrates a fully automated laboratory platform called BioAutomata that integrates robotics with machine learning to close the entire Design-Build-Test-Learn (DBTL) cycle in synthetic biology with minimal human intervention after initial setup.