Homeworktype: chapter

Weekly homework submissions:

  1. Biological Engineering Application This project proposes the development of an intestinal spheroid culture platform derived from cell lines (e.g., Caco-2 spheroid or organoid-like cultures), combined with multi-omics profiling (transcriptomics, proteomics, and metabolomics) computational modeling using systems biology and machine-learning approaches. The platform is intended to support research on drug absorption, inflammatory bowel disease (IBD) diagnostics, and predictive analysis of treatment outcomes. Initially, the system will be used to generate hypotheses from experimental data, with the long-term goal of becoming a predictive research tool.

  • Week 2 HW: DNA Read, Write, & Edit

    1-Benchling-in-silico-gel-art Using Benchling.com, Lambda DNA, Paul Vanouse’s Latent Figure Protocol artworks, and Ronan’s website as references, and incorporating creative design principles, simulations of restriction enzyme digests of the Lambda genome were performed using EcoRI, HindIII, BamHI, KpnI, EcoRV, SacI, and SalI: Figure 1. Virtual restriction digest of Lambda DNA. Once the banding patterns were characterized, images inspired by the previously mentioned works were created:

  • Week 3 HW: Lab automation

    Assignment: Python Script for Opentrons Artwork Based on the Lissajous function, the figure to be created on the agar will be the following: Post-Lab Questions — DUE BY START OF FEB 24 LECTURE Paper: Automation of biochemical assays using an open-sourced, inexpensive robotic liquid handler Moukarzel et al. 2024