Cholera Shield Engineered Spores for Rapid Cholera Protection A Engineering SuperBugs for Good! | HTGAA 2026 | 2026
The Challenge Cholera kills over 100,000 people annually across Africa, Southeast Asia, and the Middle East. Yet the disease is preventable. When an outbreak strikes, the window to act is measured in days—but conventional oral cholera vaccines (OCVs) take 2–4 weeks to deploy, require constant cold-chain logistics (2–8°C), cost $1.50–5.00 per dose, and need trained health workers to administer. By the time they arrive, transmission is already widespread.