<?xml version="1.0" encoding="utf-8" standalone="yes"?><rss version="2.0" xmlns:atom="http://www.w3.org/2005/Atom"><channel><title>Week 5 HW: Protein Design Part II :: 2026a-gabriela-frajtag</title><link>https://pages.htgaa.org/2026a/gabriela-frajtag/homework/week-05-hw-protein-design-part-ii/index.html</link><description>Part A: SOD1 Binder Peptide Design (From Pranam) Part 1: Generate Binders with PepMLM I first generated the mutated sequence: SOD1 A4V MATK**V**VCVLKGDGPVQGIINFEQKESNGPVKVWGSIKGLTEGLHGFHVHEFGDNTAGCTSAGPHFNPLSRKHGGPKDEERHVGDLGNVTADKDGVADVSIEDSVISLSGDHCIIGRTLVVHEKADDLGKGGNEESTKTGNAGSRLACGVIGIAQ
I then used the PepMLM-650M notebook to generate peptide binders conditioned on the mutant SOD1 sequence. I set the peptide length to 12 amino acids and generated candidate binders from the model output. The resulting peptides and their pseudo-perplexity values are shown below.</description><generator>Hugo</generator><language>en</language><atom:link href="https://pages.htgaa.org/2026a/gabriela-frajtag/homework/week-05-hw-protein-design-part-ii/index.xml" rel="self" type="application/rss+xml"/></channel></rss>