Homework

Week 1 HW: Principles and Practices
I would like to develop a transcription factor cocktail for the direct conversion of fibroblasts into megakarycytes - specifically platelet-producing megakaryocytes. Fibroblasts are an accessible cell type so this would be a scalable method to produce a more rare cell type for various therapeutic applications. It could also be a stepping stone for studying engineering platelets, creating a platform for stem-cell independent targeted drug delivery, clotting modulation, or tumor microenvironment sensing.