<?xml version="1.0" encoding="utf-8" standalone="yes"?><rss version="2.0" xmlns:atom="http://www.w3.org/2005/Atom"><channel><title>Week 3 HW: Lab Automation :: 2026a-joe-krushelnick</title><link>https://pages.htgaa.org/2026a/joe-krushelnick/homework/week-03-hw-lab-automation/index.html</link><description>HTGAA Week 03 - Lab Automation Find and describe a published paper that utilizes the Opentrons or an automation tool to achieve novel biological applications.
https://www.nature.com/articles/s42003-019-0305-x?utm_source=chatgpt.com
This paper used a Tecan liquid handler to enable high-throughput patient-derived tumor organoid drug screening, moving beyond pipetting into a biologically novel precision medicine application. The researchers wanted to determine whether patient-derived tumor organoids (miniature 3D tumors grown from real patient cancer tissue) could be used to rapidly identify effective anti-cancer drugs for individual patients. The Tecan system automated several otherwise tedious and error-prone steps: precise dispensing of organoid cultures into multiwell plates, automated addition of large drug libraries at multiple concentrations, and standardization of timing and reagent handling to reduce variability between samples. This helped make organoid-based drug screening much more scalable as a workflow for research.</description><generator>Hugo</generator><language>en</language><atom:link href="https://pages.htgaa.org/2026a/joe-krushelnick/homework/week-03-hw-lab-automation/index.xml" rel="self" type="application/rss+xml"/></channel></rss>