Homework

Week 1 HW: Principles and Practices
Biological Engineering Application or Tool The proposed application is an AI-guided protein therapeutic discovery and bioproduction platform. The system uses machine learning–based protein design models to generate novel therapeutic protein candidates, such as antimicrobial proteins, enzymes, or biologics optimized for stability and activity. These candidates are then evaluated for manufacturability and functional performance using controlled bioproduction workflows, including microbial expression or cell-free systems. This application reflects an emerging paradigm in biopharmaceutical development, where AI accelerates early-stage discovery while scalable bioproduction determines clinical and commercial feasibility. However, as AI enables rapid de novo protein design, many generated sequences may lack homology to known natural proteins, introducing novel biosecurity and safety risks if not properly governed.