<?xml version="1.0" encoding="utf-8" standalone="yes"?><rss version="2.0" xmlns:atom="http://www.w3.org/2005/Atom"><channel><title>Week 5 HW: Protein Design - Part 2 :: 2026a-karina-campos</title><link>https://pages.htgaa.org/2026a/karina-campos/homework/week-05-hw-protein-design-part-ii/index.html</link><description>Part A. SOD1 Binder Peptide Design
The perplexity scores for the candidate peptides were: ‘SDGAVLLGSDGE’ (Candidate 1): 16.25 ‘LLGSDGALQVGS’ (Candidate 2): 14.65 ‘SGVAVLCSDGQG’ (Candidate 3): 25.34 ‘AVGVCGVAVLGN’ (Candidate 4): 17.20
Lower perplexity scores suggest that the model finds a sequence more “familiar” or “expected,” potentially correlating with higher biological plausibility, conformational stability, or likelihood of interaction. Candidate 2, with a perplexity of 14.65, appears to be the most promising candidate from the mutated SOD1 sequence for further investigation, being closest to the known binding peptide’s score.</description><generator>Hugo</generator><language>en</language><atom:link href="https://pages.htgaa.org/2026a/karina-campos/homework/week-05-hw-protein-design-part-ii/index.xml" rel="self" type="application/rss+xml"/></channel></rss>