Week 1 HW: Principles and Practices

Ethics in medical research Ethics in medical research

A Living Anti-Corrosion System for Ocean Infrastructure:

I propose a biologically engineered, self-healing anti-corrosion coating for offshore and ocean-energy infrastructure (tidal turbines, wave energy converters, offshore wind foundations).The system uses genetically engineered, non-pathogenic marine bacteria embedded in a sealed, porous coating. These microbes are designed to:

  1. Detect early corrosion signals (pH drop, Fe²⁺ ion release)
  2. Respond by precipitating protective minerals (e.g., calcium carbonate)
  3. Neutralize corrosive microenvironments
  4. Signal early warnings before structural failure

Governance Policy Goals To ensure this application contributes to an ethical future and prevents harm, governance should pursue the following goals:

  1. Ensure safety and security: a) Prevent environmental release or misuse of engineered organisms and b) Avoid ecological disruption or biosecurity risks
  2. Promote constructive and beneficial use a) Direct innovation toward public-interest infrastructure (renewable energy, climate resilience) and b)Prevent purely extractive or environmentally harmful deployment

Action 1: Mandatory Biological Containment & Kill-Switch Standards Purpose: What is done now: Chemical anti-corrosion coatings are regulated mainly for toxicity, not biological behavior.

Proposed change: Require all engineered microbes used in marine infrastructure to include:

  1. Genetic kill switches
  2. Nutrient dependency (cannot survive outside coating)
  3. Physical encapsulation in sealed matrices
  4. Maintain transparency and public trust Design : Needed - International biosafety certification for “contained-use marine bio-systems” Assumptions: Kill switches will function reliably in harsh marine environments What could be wrong:Evolutionary escape mechanisms

Action 2: Environmental impact and Community Consent framework Purpose What is done now: Environmental Impact Assessments (EIAs) often focus on physical structures, not biological agents.

Proposed change: Require Bio-Environmental Impact Assessments (Bio-EIAs) that include:

  1. Long-term microbial ecosystem modeling
  2. Transparent disclosure of organism function
  3. Consultation with coastal and fishing communities Design: Needed- Continuous post-deployment monitoring Assumptions: Communities can meaningfully engage with technical information What could be wrong:Information asymmetry and monitoring fatigue over time

Action 3: Restricted Use Licensing (Purpose-Bound Deployment) Purpose What is done now: Biotechnologies often spread from research into unintended domains (e.g., CRISPR kits, dual-use chemicals).

Proposed change: License this technology only for defined applications:

  1. Renewable energy infrastructure
  2. Public maritime assets Design: Needed- Purpose-specific approval, audits of deployment sites and clear penalties for misuse Assumptions: Clear boundaries between “civil” and “non-civil” uses exist What could be wrong: Commercial influence to expand scope

Next, score (from 1-3 with, 1 as the best, or n/a) each of your governance actions against your rubric of policy goals. The following is one framework but feel free to make your own:

Governance ActionSafety & SecurityConstructive & Beneficial Uses
Option 1: Bio-containment standards12
Option 2: Voluntary guidelines33
Option 3: Impact & consent reviews21

Based on the scores, I would prioritize Option 1 (Bio-containment standards) together with Option 3 (Impact and community consent reviews).

Option 1 comes first because safety has to be the foundation. When we introduce engineered biological systems into the ocean, the biggest risk is that something spreads, mutates, or behaves in ways we didn’t expect. Strong bio-containment rules like built-in kill switches or limits on survival outside controlled conditions help prevent accidents before they happen. Without this layer, even well-intended projects could cause long-term environmental harm.

Option 3 is equally important because it helps make sure the technology is actually used for good. Environmental impact checks and community consent force developers to think beyond the lab and consider real ocean ecosystems and the people who depend on them. This option scored highest for promoting constructive and beneficial uses because it guides innovation toward solutions that are socially and environmentally responsible, not just technically impressive.

I would not rely on Option 2 (Voluntary guidelines) on its own. While voluntary rules can encourage early innovation, they are easy to ignore and don’t offer strong protection when risks are high. For ocean systems, where damage can be difficult or impossible to reverse, voluntary measures are not enough.

Overall, combining strong safety rules with environmental and community oversight offers the most realistic and responsible way to move forward. It protects the ocean while still allowing beneficial innovation to happen.

References:

  1. Jin, H., Wang, J., Tian, L., Gao, M., Zhao, J., & Ren, L. (2022). Recent advances in emerging integrated antifouling and anticorrosion coatings. Materials & Design, 213, 110307. https://doi.org/10.1016/j.matdes.2021.110307

  2. Li, Y., & Ning, C. (2019). Latest research progress of marine microbiological corrosion and bio-fouling, and new approaches of marine anti-corrosion and anti-fouling. Bioactive Materials, 4, 189–195. https://doi.org/10.1016/j.bioactmat.2019.04.003