Projects

Brainstorms
Melanin-based bioink for Light-Recording Materials My individual final project is based on melanin and related compounds in an engineered living material (ELM) as a color-responsive bio-ink. Among many other factors, oxidation state, precursor availability / intermediate reaction pathways likely shape tone and long-term stability and may be modulated using a genetic system, be it a bacterium, a synthetic minimal cell, etc.
Individual Final Project: Melanin-based light-recording bioink/biomaterial
Important links: Commited Listener Slide Deck here. Benchling (TO BE ADDED) Asimov Kernel (TO BE ADDED) Aim 1: Build a first melanin-producing cell-free DNA module based on melA tyrosinase + Define validation parameters The melA gene is coding sequence of tyrosinase that catalizes the conversion of tyrosine to dopaquinone. Dopaquinone is intermediate product of melanin biosynthesis pathway that polymerizes in an enzyme-independent reaction to form melanin.
Group Final Project
Bacteriophage Engineering GROUP MEMBERS: Diogo Custodio; Flo Razoux; Katharine Kolin; Mariana Kanbe; Marisa Satsia. PROJECT MAIN GOAL : Increase the stability of the L protein GROUP PROPOSAL: We will use the same workflow than in previous HW (e.g. mutagenesis) but adapt it to specific aim(s) based on HW reading material of week 04 (e.g. shorten the L protein to make it not dependant on bacterial chaperone DnaJ anymore).