<?xml version="1.0" encoding="utf-8" standalone="yes"?><rss version="2.0" xmlns:atom="http://www.w3.org/2005/Atom"><channel><title>Week 5 HW: Protein Design Part II :: 2026a-mariia-moshchenskaia</title><link>https://pages.htgaa.org/2026a/mariia-moshchenskaia/homework/week-05-hw--protein-design-part-ii/index.html</link><description>Part A: SOD1 Binder Peptide Design (From Pranam)
Part 1: Generate Binders with PepMLM
The amino acid sequence of the human SOD1 protein was taken from the UniProt database (ID: P00441), and the A4V mutation was introduced. Amino acid sequence of the human SOD1 protein from UniProt (ID: P00441):
MATKAVCVLKGDGPVQGIINFEQKESNGPVKVWGSIKGLTEGLHGFHVHEFGDNTAGCTSAGPHFNPLSRKHGGPKDEERHVGDLGNVTADKDGVADVSIEDSVISLSGDHCIIGRTLVVHEKADDLGKGGNEESTKTGNAGSRLACGVIGIAQ
The A4V mutation was introduced:
MVTKAVCVLKGDGPVQGIINFEQKESNGPVKVWGSIKGLTEGLHGFHVHEFGDNTAGCTSAGPHFNPLSRKHGGPKDEERHVGDLGNVTADKDGVADVSIEDSVISLSGDHCIIGRTLVVHEKADDLGKGGNEESTKTGNAGSRLACGVIGIAQ
Four peptides of 12 amino acids in length were generated based on the mutant SOD1 gene sequence.</description><generator>Hugo</generator><language>en</language><atom:link href="https://pages.htgaa.org/2026a/mariia-moshchenskaia/homework/week-05-hw--protein-design-part-ii/index.xml" rel="self" type="application/rss+xml"/></channel></rss>