https://pages.htgaa.org/2026a/moukthika-pinnamreddy/homework/week-01-hw-principles-and-practices/index.htmlFirst, describe a biological engineering application or tool you want to develop and why. This could be inspired by an idea for your HTGAA class project and/or something for which you are already doing in your research, or something you are just curious about.Hugoenhttps://pages.htgaa.org/2026a/moukthika-pinnamreddy/homework/week-01-hw-principles-and-practices/week-02-lecture-prep/index.htmlMon, 01 Jan 0001 00:00:00 +0000https://pages.htgaa.org/2026a/moukthika-pinnamreddy/homework/week-01-hw-principles-and-practices/week-02-lecture-prep/index.htmlHomework Questions from Professor Jacobson 1. Nature’s machinery for copying DNA is called polymerase. What is the error rate of polymerase? How does this compare to the length of the human genome. How does biology deal with that discrepancy? According to Albertson & Preston (2006), it is estimated that replicative DNA polymerases make errors approximately once every 10⁴–10⁵ nucleotides polymerized; i.e. the error rate is 10⁻⁴ to 10⁻⁵, before proofreading and post‑replicative repair. The human genome is roughly 3 billion base pairs (3 × 10⁹) (Cooper, 2000, The Human Genome).