Homework
Weekly homework submissions:
Week 1 HW: Principles and Practices
Homework Week 1 Biological Engineering Application First, describe a biological engineering application or tool you want to develop and why. This could be inspired by an idea for your HTGAA class project and/or something for which you are already doing in your research, or something you are just curious about.
Homework Week 1, Lecture Prep Homework Questions from Professor Jacobson: Nature’s machinery for copying DNA is called polymerase. What is the error rate of polymerase? How does this compare to the length of the human genome. How does biology deal with that discrepancy?
Week 2 HW: DNA Read Write and Edit
Part 1: Benchling & In-silico Gel Art Here is a run of all the enzymes we were told to use in our virtual digest on benchling. Here is an ‘art run’ of the virtual digest, I think this looks like an elephant. Part 2: Gel Art - Restriction Digests and Gel Electrophoresis
Lab Automation Design links: http://opentrons-art.rcdonovan.com/?id=14ylm4e9u480k3w http://opentrons-art.rcdonovan.com/?id=jsx1tq762tv3s6q Post-Lab Questions Find and describe a published paper that utilizes the Opentrons or an automation tool to achieve novel biological applications. Malcı, K., Meng, F., Galez, H., Franja Da Silva, A., Caro-Astorga, J., Batt, G. and Ellis, T., 2026. Slowpoke: An Automated Golden Gate Cloning Workflow for Opentrons OT-2 and Flex. ACS Synthetic Biology.