Homework
Weekly homework submissions:
Week 1 HW: Principles and Practices
Multimodal Assistive Communication System for Nonverbal Users Proposed Bioengineering Application I plan to focus on developing a multimodal assistive communication system for nonverbal users that integrates speech, gestures, and biological signals such as muscle activity or eye movement. The goal of this system is to help individuals with communication disorders express themselves more accurately and autonomously by leveraging whichever input methods are most reliable for them. The reason I want to go through with this topic is because I personally believe that it closely connects to my interests in Human-Computer Interaction and is a project where the concepts of Bioengineering would highly benefit it.
Week 2 HW: DNA Read, Write and Edit
Part 1: Benchling and In-Silico Gel Art I made a Benchling accountand imported the Lambda DNA genbank sequence from https://www.ncbi.nlm.nih.gov/nuccore/J02459.1?report=genbank&log$=seqview After importing everything I used Benchling’s Digest tool to stimulate the enzyme digestion of the Lambda DNA using the required enzymes. I first made all of the enzymes that were asked in the list.
Homework Questions from Professor Jacobson Nature’s machinery for copying DNA is called polymerase. What is the error rate of polymerase? How does this compare to the length of the human genome. How does biology deal with that discrepancy? The error rate of DNA polymerase with proofreading has an error rate of approximately 1 error per 10⁶ base pairs copied (10⁻⁶ per base). The human genome is ~3.2 billion base pairs (3.2 × 10⁹ bp). If polymerase made errors at 1 in 10⁶ bases, then you would expect roughly ~3,200 errors per genome replication. Biology uses multiple layers of error correction:
Python Script for Opentrons Artwork from opentrons import types import math metadata = { ‘author’: ‘Shubhadip Saha’, ‘protocolName’: ‘H+S’, ‘description’: ‘A heart with the letters H+S inside of it.’, ‘source’: ‘HTGAA 2026 Opentrons Lab’, ‘apiLevel’: ‘2.20’ } TIP_RACK_DECK_SLOT = 9 COLORS_DECK_SLOT = 6 AGAR_DECK_SLOT = 5 PIPETTE_STARTING_TIP_WELL = ‘A1’ well_colors = { ‘A1’ : ‘Red’, ‘B1’ : ‘Green’, ‘C1’ : ‘Orange’ }