Individual Final Project
A post-mitotic asymmetric condensate disassembly module for autonomous state bifurcation
The project is, essentially, about a system that is able to generate one, or very few, condensates, that upon cell division, release their content in the cells that inherited the condensate. This content could be mRNAs of different transcription factors that are able to drive cell-fate differentiation. This proposes to be an step to unlock the potential of autonomous cell-fate differentiation, an essential tool for multicellularity, in synthetic multicellular systems.
This project is divided in two sub-projects: the post-mitotic activation circuit and the single condensate formation.
A detail description of the project is discused in the following card. Next is the individual final project documentation required.
- ¿How would it work? ¿What are the components? ¿Why those components?