Projects

Final projects:

Final Group Project Module →

Access project documentation and source files

Technical Roadmap

1. DnaJ-Independent Mutagenesis

  • Site Identification: Targeting 4 residues in the lysis protein.
  • Engineering: Mutating to remove DnaJ dependency.
  • Validation: Verifying activity across diverse environments.

2. De Novo Protein Design

  • Optimization: Designing for a “mild yet potent” profile.
  • Precision Control:
    • Intensity: Enhancing lytic strength for efficacy.
    • Timing: Calibrating thresholds for accurate release.
  • Clinical Safety: Balancing clearance and host-cell impact.