https://pages.htgaa.org/2026a/taliana-vyaltseva/homework/week-05-hw-protein-design-part-ii/index.htmlPart A: SOD1 Binder Peptide Design (From Pranam) Part 1: Generate Binders with PepMLM MATKAVCVLKGDGPVQGIINFEQKESNGPVKVWGSIKGLTEGLHGFHVHEFGDNTAGCTSAGPHFNPLSRKHGGPKDEERHVGDLGNVTADKDGVADVSIEDSVISLSGDHCIIGRTLVVHEKADDLGKGGNEESTKTGNAGSRLACGVIGIAQ Part 2: Evaluate Binders with AlphaFold3 HRYGAVVVELKK Structure Based on the image you provided: · ipTM score = 0.4 · pTM score = 0.86 The peptide (residues shown along the vertical axis, roughly 1–165) appears to bind along one face of the folded protein domain, but the alignment confidence (pLDDT coloring) is mixed. There is a very low confidence (dark orange/red) stretch around residues ~33–66 and again near ~132–165, suggesting the predicted binding mode may be unreliable in those regions.Hugoen