https://pages.htgaa.org/2026b/adriana-suarez/index.htmlAbout me I am an undergraduate student from Cochabamba, Bolivia. I am currently in my third year of Bioengineering, with previous studies in Biology. I love exploring topics related to astrobiology and space biomedicine. However, I also constantly enjoy expanding my knowledge into different areas of my career. Thus, through this page, I will delve deeper into neurological diseases, particularly Sanfilippo syndrome, not only to raise awareness about rare diseases, but also to contribute to science and learn more about how biomanufacturing can help us better understand these conditions.Hugoenhttps://pages.htgaa.org/2026b/adriana-suarez/week-01-hw-project-ideas/index.htmlMon, 01 Jan 0001 00:00:00 +0000https://pages.htgaa.org/2026b/adriana-suarez/week-01-hw-project-ideas/index.htmlBiomanufacturing Human Neural Models for Neurodegenerative Disease Research (1) What would I like to biomanufacture and why? I would like to biomanufacture standardized three-dimensional human neural disease models. Their main objective would be to study neurological disorders and, in the future, evaluate potential therapies. More specifically, I am interested in developing a reproducible platform for producing small neural tissue models that capture selected features of human neural tissue, with lysosomal storage disorders as one of the main applications. One example of these conditions that I would like to work on is Sanfilippo syndrome. Scientifically known as mucopolysaccharidosis type III (MPS III), Sanfilippo syndrome occurs when the degradation of heparan sulfate is impaired, leading to its accumulation and contributing to cellular dysfunction, particularly in the central nervous system [1]. As a result, patients progressively lose cognitive and motor skills. In this regard, the models would be intended for researchers studying neurological disorders, including rare and understudied conditions, allowing them to compare healthy and disease-associated neural phenotypes and test potential treatments under controlled and reproducible conditions. I am particularly interested in this idea because neurological disorders affect millions of people worldwide every year and can have a profound impact on quality of life. From widely recognized conditions such as Alzheimer’s disease to rare and less well-known disorders such as Sanfilippo syndrome, these conditions have very different causes and mechanisms, but they can all affect the nervous system and significantly alter the lives of not only patients but also their families and caregivers. Even when a condition affects a relatively small number of people, its impact can be substantial because of the progressive nature of many neurological disorders and the limited treatment options available. For this reason, I am interested in developing human neural models that could help researchers better understand these disorders and contribute to feasible solutions with meaningful real-world impact.https://pages.htgaa.org/2026b/adriana-suarez/week-02-hw-dna-design/index.htmlMon, 01 Jan 0001 00:00:00 +0000https://pages.htgaa.org/2026b/adriana-suarez/week-02-hw-dna-design/index.htmlhttps://pages.htgaa.org/2026b/adriana-suarez/final-project/index.htmlMon, 01 Jan 0001 00:00:00 +0000https://pages.htgaa.org/2026b/adriana-suarez/final-project/index.html