https://pages.htgaa.org/2026b/carla-veronica-fuenteslopez/index.htmlHugoenhttps://pages.htgaa.org/2026b/carla-veronica-fuenteslopez/week-01-hw-project-ideas/index.htmlMon, 01 Jan 0001 00:00:00 +0000https://pages.htgaa.org/2026b/carla-veronica-fuenteslopez/week-01-hw-project-ideas/index.html(1) What I would like to biomanufacturer and why Target: A multi-chamber microfluidic “joint-on-a-chip” device that co-cultures cartilage tissue (chondrocytes), vascular tissue (endothelial cells), and peripheral nerve tissue (neural cells) in adjacent chambers, connected by a shared microchannel perfused with human synovial fluid under physiological shear. Both the chip itself and the chip-co-culture platform are the manufactured products. This configuration is designed specifically to model the cartilage–nerve–vasculature axis underlying joint pain, as distinct from a purely inflammatory/immune model; adding an immune cell compartment (e.g., macrophages) is noted here as a possible future extension rather than part of the current design.https://pages.htgaa.org/2026b/carla-veronica-fuenteslopez/week-02-hw-dna-design/index.htmlMon, 01 Jan 0001 00:00:00 +0000https://pages.htgaa.org/2026b/carla-veronica-fuenteslopez/week-02-hw-dna-design/index.htmlDefining Expression Target Designing Genetic Parts Assembling the Construct Optimisation & Quality Check From Design to Build What I don’t know yet Declarations & Noteshttps://pages.htgaa.org/2026b/carla-veronica-fuenteslopez/week-03-hw-cell-free/index.htmlMon, 01 Jan 0001 00:00:00 +0000https://pages.htgaa.org/2026b/carla-veronica-fuenteslopez/week-03-hw-cell-free/index.html3. ASSIGNMENT: CFPS REACTION DESIGN FOR SFGFP, PETASE, RETEPLASE Goal: using the collective intelligence of the HTBAA community and accessible AI systems, design novel CFPS reaction compositions for each of the three target proteins: sfGFP, PETase, and Reteplase to reduce the cost per gram of functional protein. Each design should be compatible with the experimental framework described above and should reflect the distinct expression and folding requirements of that protein. You can learn more about the details of the coopetition here.https://pages.htgaa.org/2026b/carla-veronica-fuenteslopez/final-project/index.htmlMon, 01 Jan 0001 00:00:00 +0000https://pages.htgaa.org/2026b/carla-veronica-fuenteslopez/final-project/index.html