<?xml version="1.0" encoding="utf-8" standalone="yes"?><rss version="2.0" xmlns:atom="http://www.w3.org/2005/Atom"><channel><title>Week 1 HW: Final Project Ideas :: 2026a-david-morales</title><link>https://pages.htgaa.org/2026b/david-morales/week-01-hw-project-ideas/index.html</link><description>1. What do you want to make? I want to biomanufacture a pair of orthogonal synthetic cell-adhesion proteins designed for directed synaptogenesis: 1SZ-Nrxn1β (presynaptic): β-neurexin scaffold fused to a synthetic SynZip coiled-coil domain. 2SZ-Nlgn1 (postsynaptic): neuroligin-1 scaffold fused to the complementary SynZip domain.&#10;These proteins act as a programmable “molecular Velcro” that preferentially drives the formation of specific synapses between neurons expressing the matching pair, overcoming the random connectivity of native neurexin–neuroligin interactions. Why?</description><generator>Hugo</generator><language>en</language><atom:link href="https://pages.htgaa.org/2026b/david-morales/week-01-hw-project-ideas/index.xml" rel="self" type="application/rss+xml"/></channel></rss>