https://pages.htgaa.org/2026b/dominic-orozco/index.htmlAbout me I’m Dominic Uriel Orozco Salgado, an undergraduate Biomedical Engineering student at Universidad de Guadalajara (2023–present), with a prior technical degree in Pharmaceutical Chemistry from CETI (2019–2023). I currently work as an Undergraduate Researcher in Biofabrication and Research Assistant in the Department of Translational Bioengineering / Biodigital Innovation Lab.Hugoenhttps://pages.htgaa.org/2026b/dominic-orozco/week-01-hw-project-ideas/index.htmlMon, 01 Jan 0001 00:00:00 +0000https://pages.htgaa.org/2026b/dominic-orozco/week-01-hw-project-ideas/index.htmlFigure adapted from Nguyen et al. (2021): the wearable freeze-dried cell-free (wFDCF) sensor platform. (a–c) Sensor architecture — a flexible, multi-layer textile insert containing freeze-dried reaction wells that activate on liquid exposure. (d–g) Four genetic-circuit designs (constitutive expression, transcriptional regulation, a toehold switch, and a riboswitch) with their colorimetric readouts over time. Source: Nguyen, P. Q., Soenksen, L. R., Donghia, N. M., Angenent-Mari, N. M., de Puig, H., Huang, A., Lee, R., Slomovic, S., Galbersanini, T., Lansberry, G., Sallum, H. M., Zhao, E. M., Niemi, J. B., & Collins, J. J. (2021). Wearable materials with embedded synthetic biology sensors for biomolecule detection. Nature Biotechnology, 39(11), 1366–1374. https://doi.org/10.1038/s41587-021-00950-3. Reproduced here for educational, non-commercial coursework use — confirm the journal’s reuse terms before publishing this repository publicly.https://pages.htgaa.org/2026b/dominic-orozco/week-02-build-in-kernel/index.htmlMon, 01 Jan 0001 00:00:00 +0000https://pages.htgaa.org/2026b/dominic-orozco/week-02-build-in-kernel/index.htmlThe Circuit Behind the Color Change Part 0: Set up in Kernel Workspace: HTGAA 2026 · Repository / Folder: Dominic Orozco_TX-TL Part 1: Define Your Expression Target What molecule am I expressing? Two proteins, working together as a sense-and-report pair, rather than an enzyme that builds a material directly. FrmR is the sensing element — a transcriptional repressor. mCherry is the reporter — a red fluorescent protein that provides the visible/measurable output. Neither protein synthesizes the physical fiber itself (that’s a materials-science step, not a biological one); the biology’s job here is purely informational: turn “formaldehyde present” into “visible red signal.”https://pages.htgaa.org/2026b/dominic-orozco/final-project/index.htmlMon, 01 Jan 0001 00:00:00 +0000https://pages.htgaa.org/2026b/dominic-orozco/final-project/index.html