https://pages.htgaa.org/2026b/muhammad-ridwan-adyatama/index.htmlAbout me ORCID ID: 0009-0007-5669-1508 Profession (veterinary medicine) student with interest in genome mining and bioprospecting of marine microbiome microorganism for biomanufacturing of novel drugs. He previously isolated coral-associated bacteria with anti-MRSA secondary metabolite for bioprospecting of novel antimicrobial. As a bachelor of veterinary medicine (S.K.H.) graduate, he is also passionate about One Health and wildlife conservationHugoenhttps://pages.htgaa.org/2026b/muhammad-ridwan-adyatama/week-01-hw-project-ideas/index.htmlMon, 01 Jan 0001 00:00:00 +0000https://pages.htgaa.org/2026b/muhammad-ridwan-adyatama/week-01-hw-project-ideas/index.htmlA 2 Step Biomanufacturing System of Synthetic Coral Mucus for Marine Drug Bioprospecting from Coral-Associated Bacteria Figure 1. Visual abstract of the project (1) What you would like to biomanufacture and why? I want to make a synthetic coral mucus platform that can reproduce the important physical and chemical properties of coral mucus without having to continuously collect mucus from living corals. My main reason for making this is related to coral-microbe interactions in the context of coral-associated microorganism bioprospecting. The presence of coral mucus affects secondary metabolite production of its associated microbial community. This challenges bioprospecting research of coral-associated microorganism, as it is often non-viable or doesn’t produce wanted metabolite in conventional culture condition. However, natural mucus is biologically complex and can vary depending on coral species, environmental conditions, and physiological state. This makes it difficult to use natural mucus as a standardized material for experiments.https://pages.htgaa.org/2026b/muhammad-ridwan-adyatama/week-02-hw-dna-design/index.htmlMon, 01 Jan 0001 00:00:00 +0000https://pages.htgaa.org/2026b/muhammad-ridwan-adyatama/week-02-hw-dna-design/index.htmlRepository : Muhammad Ridwan Adyatama Part 1: Define your expression target 1. What molecule are you expressing? A protein, an RNA, or an enzyme (or small set of enzymes) for a pathway. If your HW1 product is a material, food, or chemical, identify the protein(s) that produce it and design for those. A recombinant protein. An unglycosylated coral mucin-like scaffold designed for subsequent in vitro enzymatic glycosylation. This is the protein backbone that will be added with coral species-specific glycans in the next step of biomanufacturing using cell-free system.https://pages.htgaa.org/2026b/muhammad-ridwan-adyatama/week-03-hw-cell-free/index.htmlMon, 01 Jan 0001 00:00:00 +0000https://pages.htgaa.org/2026b/muhammad-ridwan-adyatama/week-03-hw-cell-free/index.htmlASSIGNMENT: CFPS REACTION DESIGN FOR SFGFP, PETASE, RETEPLASE Goal: using the collective intelligence of the HTBAA community and accessible AI systems, design novel CFPS reaction compositions for each of the three target proteins: sfGFP, PETase, and Reteplase to reduce the cost per gram of functional protein. Each design should be compatible with the experimental framework described above and should reflect the distinct expression and folding requirements of that protein.https://pages.htgaa.org/2026b/muhammad-ridwan-adyatama/final-project/index.htmlMon, 01 Jan 0001 00:00:00 +0000https://pages.htgaa.org/2026b/muhammad-ridwan-adyatama/final-project/index.html