2026a-tammy-sisodiya
How To Biomanufacture (Almost) Anything · Fall 2026
Tammy Sisodiya
Designing proteins (de novo proteins & redesigned proteins with new and innovative functions!) on a laptop, and slowly learning how to grow them for real.
About me
Hello, and thank you for stopping by. I’m Tammy, a researcher based in the UK, working somewhere in between computational protein design, synthetic biology, and drug delivery. My background is in biology, with a foundation in cancer immunology, and a lot of what I do now begins at a laptop: designing proteins, thinking about lipid nanoparticle formulations, and writing small tools to make the fiddly parts of research a little kinder.
What keeps pulling me back towards the bench is the moment a design has to survive contact with something living. Outside of my own research I have spent time at Lifefabs, a community biology lab in London, and I came into this course by way of HTGAA (Spring 2026), which I followed as a global listener. It was the first time I watched a whole room treat “could we actually make that?" as a reasonable question, and I have been chasing that feeling ever since.
I am taking HTBAA because designing a molecule is only half of the story. The other half — how you actually produce it, reliably, at a scale past a single tube — is the part I most want to get better at.
What I am curious about this term
From screen to strain
Getting a designed protein out of a computer and into something that will actually express, fold, and behave.
Cell-free systems
How far a cell-free reaction will carry you before you genuinely need a fermenter — and how you can tell.
Formulation & delivery
The point where biology begins to look like chemical engineering, and a nanoparticle has to hold together.
Protocols that travel
Writing things up openly enough that somebody else can pick them up and reach the same result.
Contact info
I am always glad to hear from people working on similar things — do say hello.
Homework, Labs, and Projects
Everything I make for How To Biomanufacture (Almost) Anything lives in the navigation bar to the left — weekly assignments, lab notes, and the longer project work as it takes shape.
I try to write these up honestly, including the things that did not work the first time, in the hope that they are useful to whoever comes next.