<?xml version="1.0" encoding="utf-8" standalone="yes"?><rss version="2.0" xmlns:atom="http://www.w3.org/2005/Atom"><channel><title>Week 2 HW: DNA Design :: 2026a-wissal-abderrahmani</title><link>https://pages.htgaa.org/2026b/wissal-abderrahmani/week-02-hw-dna-design/index.html</link><description>Building the GD2-SynNotch–GPC2 CAR-T Genetic Circuit This week, I translated the therapeutic concept proposed in Homework 1 into defined genetic parts and three buildable lentiviral constructs.&#10;GD2 sensing → SynNotch activation → GPC2-CAR + EGFP expression → GPC2 recognition → T-cell activation + mbIL-15 support 1. 🧬 Define the expression target 1.a What molecules am I expressing? For my project, I will express two synthetic receptors (GD2-SynNotch and GPC2-CAR), one membrane-tethered cytokine (IL-15), and a fluorescent reporter (EGFP).</description><generator>Hugo</generator><language>en</language><atom:link href="https://pages.htgaa.org/2026b/wissal-abderrahmani/week-02-hw-dna-design/index.xml" rel="self" type="application/rss+xml"/></channel></rss>